Synthesis, Characterization and Biological Screening of Oxadiazole Incorporated Acetamide Derivatives as Potent Antibacterial Agents

Author(s): Jayesh P. Jadhav, Maharshi B. Shukla, Anil T. Mahato & Kokila A. Parmar

A series of ten derivatives of 2-[(5-aryl-1,3,4-oxadiazol-2-yl)sulfanyl]-N-(2,4,6-tribromophenyl)acetamide was synthesized and the structure of synthesized compounds were determined by obtained IR,1H NMR andMass spectroscopy data. To evaluate biological potential of synthesized compounds they were subjected for invitroantibacterial study against gram positive bacterial strains Staphylococcus aureus,Bacillus subtilis and gram negative bacterial strainsPseudomonas aeruginosa, Escherichia coliwhere antibacterial potential was shown by some compounds.


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