ABSTRACT: Spirulinaplatens is the cyanobaceteria,otherwise known as blue green alga is common in fresh water bodies generally found in alkaline saline water. Spirulina is significantly effective not only in keeping good health but also in improving various symptoms of disease. Spirulina ash contained a number of inorganic and organic, sodium, potassium, phosphorus and vitamin A, Vitamin E (tocophyrol), Vitamin B12 and B6etc. like complexes. Subject’s obesity patients were 100 patients,50 male and 50 female candidates for 45 days. Initially before start the methodology primary observation and anthropometric measurement were would be taken and WHR (waist and hip ratio), Bloodpressure, Hb, hypercholestemia, Diabetic,PCOD,menopause,stress with obesitysubjects for100 patients age around 18 to 70 years both male and female. Subjects were divided in 2 groups according gender male female patients data. As per results they were reduced 3 kg weight and improved sleeping quality also. Spirulina L-Tryptophan is naturally found in animal and plant, it is very essential amino acid because its protein building block. Itisvery essential amino acid andbody cannot makeit so itmust requireinfood. Tryptophan is important for the development and functioning of many organismofthe body. After absorbing L-tryptophan from food, our bodies convert it to 5-HPT (5 hydroxytryptophane)and then to serotonin, melatonin and vitamin B6 (nicotinamide). Sero-tonin is a hormone that transmits signals between nerve cells. It’s also causes blood vessels to narrow change in the level of serotonin in the brain can alter mood and feel like satisfaction and satiety. Melatonin is playing important part for sleep and vitamin B6 is essential for metabolism.