Pyrazoles have played an important part in the progression of theory in heterocyclic chemistry and also used extensively in organic synthesis. Pyrazoles are five membered heterocyclic compounds. Compounds which containing pyrazole derivatives are well-known and important nitrogen-containing five-membered heterocyclic compounds. Among the two nitrogen atoms; one is basic and the other is neutral in nature. Pyrazole and its deriva-tives have displayed broad spectrum of pharmacological important active scaffold that possesses almost all types of pharmacological activities and biological activities such as antimicrobial, antitumor, antiviral, antidepressant, anti-convulsant, antihyperglycemic, and enzymes inhibitory activities. Present paper is emphasizes on microwave as-sisted synthesis of some schemes Pyrazole Derivatives.