Volume 5 Issue 1

Publication starts from January, 2019 to June, 2019)

Sr. No. Title Author’s Name(s) Abstract Page Nos. Article
1. Synthesis of Innovative Thiolated Red Toon Lignin for the Removal of Fe(III) from Aqueous System Vishal Priya, Pankaj Sharma and Divya Vishambra In the present work, thiomer have been synthesized via thiourea reactions in high degree of modification and degree of substitution is 2.1. Preparation of polymer follows green chemistry protocol with respect to green solvent utilization and zero waste generation. The thiol products are responsive for further derivatization and were modified to a sulphide. The above mentioned reactions were also carried out using microwave heating to achieve maximum yet uniform modification of red toon lignin. The extent of the derivatization processes was confirmed by iodine titration and precipitation titration.Click Here To Read More 01-10 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.001

2. Nutritional Influence (Spirulina) of Biochemical and Obese Stress Patients Deepika Pancholi and Ikram Qureshi Spirulina platens is the cyanobaceteria, otherwise known as blue green alga is common in fresh water bodies generally found in alkaline saline water. Spirulina is significantly effective not only in keeping good health but also in improving various symptoms of disease. Spirulina ash contained a number of inorganic and organic, sodium, potassium, phosphorus and vitamin A, Vitamin E (tocophyrol), Vitamin B12 and B6 etc. like complexes. Subject’s obesity patients were 100 patients, 50 male and 50 female candidates for 45 days.Click Here To Read More 11-13 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.002

3. An Overview of In Situ Gel Forming Implants: Current Approach Towards Alternative Drug Delivery System Nirmala Musmade, Anil Jadhav, Priyanka Moin, Suvarna Patil and Akhilesh Gupta Usually, researchers find the difficulties for the development of novel drug delivery systems by implementing the novel technologies. Also there are lots of challenges to make these systems site specific for effective drug delivery for extended period of time. A novel biodegradable, injectable polymeric system namely in-situ forming implants (ISFIs) looks very promising drug delivery system. In-situ gel formation of drug delivery systems can be defined as a liquid formulation generating a solid or semisolid depot after administration. It is a blend of drug and biodegradable polymers dissolved or suspended in pharmaceutically acceptable water-miscible organic solvents.Click Here To Read More 14-21 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.003

4. To Study Characterization and Antibacterial Activity of Bacteriocin Producing Lactobacillus Isolated from Curd Manish Agarwal, Arun Kumar and Ikram Qureshi The present study is carried out with the lactic acid bacteria isolation and identification such as Lactobacillus fermentum from curd sample. Five isolates of Lactobacilli supernatant is examined for acid and antibacterial activity production. The extracted compound showed antibacterial activity against the microorganisms. Lactobacillus fermentum showed better antimicrobial activity. Antibacterial activities LAB are dietary supplements of live microorganisms thought to be healthy for the host organisms. In this study, lactic acid bacteria are isolated from 2 different curd samples.Click Here To Read More 22-26 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.004

5. Synthesis of Some Novel N-alkylated 2-chloro-Benzimidazole Derivatives and their Biological Evaluation Ashish Yasin Hawaldar and Sanjay Dashrath Vaidya A series of novel N-substituted benzimidazole derivatives have been synthesized by the condensation of ortho-phenylenediamine and urea, subsequent reaction of the product obtained with Phosphoryl chloride to give 2-Chloro-1H-benzimidazole. Using this compound alkylation done at the benzimidazole –NH position with different benzyl halide reagent leading to the functionalized derivatives.Click Here To Read More 27-31 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.005

6. Computation of Thermoacoustic and Thermodynamic Properties of Aqueous Methyl Orange Solution from Density and Sonic Speed Data J. D. Pandey1, Rupali Sethi, Subhash Chandra Shrivastava, Vandna Pathak and S. K. Vishwakarma Density and ultrasonic speed data have been used to calculate a number of useful and important thermoacoustic and thermodynamic parameters such as thermal expansivities, α, isothermal compressibility, βT, internal pressure, Pint, specific heat ratio, ϒ, surface tension, σ, Pseudo-Grüneisen parameter, Г, non-linearity parameter, B/A, by empirical relations at T= (303, 308, 313 and 318) K temperatures in the range concentration from 0.05 to 1 molar.Click Here To Read More 32-37 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.006

7. Phytochemical Analysis of Ocimum americanum Linn. with Special Reference to the Impact of In vitro Flowering on the Production of Aromatic Compounds Pranab Giri Apart from chavicol, methyl chavicol, camphor and linalool another major compound cineole is typically present in a very high amount in the essential oil of Ocimum americanum growing in different agro climatic region of West Bengal. Conventionally Cineole (1,8 Cineole) is obtained from sufficiently matured Eucalyptus sp. The article deals with the efficiency of the in vitro mass propagation of this species as a strategy of alternative cheaper way of commercial production of the aromatic compounds as a constituent of essential oil.Click Here To Read More 38-42 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.007

8. Some Filamentous Blue Green Algae from Sukhana Dam, Aurangabad, Maharashtra Sampada K. Shejul and R. J. Sawant Algae from Sukhana dam, Aurangabad were investigated from 2015-2017. Algal samples were collected from 3 different locations of the water body. Several taxa belonging to class Chlorophyceae, Bacillariophyceae, Cyanophyceae and Euglenophyceae were observed. In the present study 21 species of genus Oscillatoria, belonging to class Cyanophyceae were observed. These are Oscillatoria acuta, O. annae, O. bornetii, O. brevis var. non granulata, O. calcuttensis, O. chalybea, O. chilkensis, O. cortiana, O. curviceps, O. fracta, O. jenensis, O. limosa, O. mougeotia, O. nigra, O. ornate var. Crassa, O. perornata, O. sancta, O. simplicissima, O. subbrevis, O. tenuis, O. vizagapatensis.Click Here To Read More 43-46 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.008

9. Analytical Method Development and Validation for Estimation of Metformin in Bulk and Pharmaceutical Dosage Form by UV Spectrometric Method Mayur Patni and Swati Rawat A rapid, simple, selective and precise UV- Visible Spectrophotometric method has been developed for the determination of metformin hydrochloride in bulk forms and tablet dosage formulations. The spectrophotometric detection was as per carried out at an absorption maximum of 232 nm using phosphate buffer of pH 6.8 as solvent. The method was validated for specificity, linearity, accuracy, precision, robustness and ruggedness. The detector response for was linear over the selected concentration range 2 to 12μg/ml with a correlation coefficient of 0.994.Click Here To Read More 47-51 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.009

10. Ultrasound Assisted Regioselective Synthesis of Polyhydrospiro [indoline-3,3’-pyrrolizine]-2-one Library via Multicomponent Cycloaddition Reaction Vishwa Deepak Tripathi Present work demonstrates the ultrasound mediated synthesis of new Hexahydrospiro[indoline-3,3’-pyrrolizine]-2-one derivatives in excellent yields via [3+2] cycloaddtion reaction in regioselective manner under ultrasonic irradiation. Multicomponent reaction of substituted 3-cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-one, isatin, L-proline was utilized for synthesis of spiro framework in regioselective manner at room temperature. All the synthesized hexahydrospiro molecules were characterized by 1H and 13C NMR, IR spectra, mass spectra and elemental analysis.Click Here To Read More 52-60 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.010

11. Synthesis, Characterization and Antimicrobial Evaluation of Ru(II) and Co(III) Complexes of Phenylene-1,2-bis(iminoflavone) Derivatives Ashok Kumar Singh, Suresh Kumar Patel and Asif Jafri Bioactive ruthenium and cobalt scaffolds of molecular formula [Ru(PPh3)2L1-4] and [Co(H2O)Cl L1-4] {where L1-4 represents the tetradentate ligands (E)-4-((2-((E)-(3-hydroxy-2-(4 substitutedphenyl)-4a,8a-dihydro-4Hchromen-4-ylidene)amino)phenyl)imino)-2-(4-substituted phenyl)-4H-chromen-3-ol (phenylenebis(iminoflavone)} have been synthesized from Ru(II) precursor [Ru(PPh3)4Cl2] and CoCl2.3H2O and phenylenebis(iminoflavone). Tetradentate ligands of flavone (phenylenebis(iminoflavone)) have been derived by the condensation of 3-hydroxy-2-(4-substitutedphenyl)-4H-chromen-4-one with o-phenylenediamine.Click Here To Read More 61-70 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.011

12. Synthesis, Characterization and Biological Screening of Quinoline Linked Oxadiazole Derivatives as Potent Antibacterial Agents Jayesh P. Jadhav, Kokila A. Parmar, Shailesh C. Kotval, Tessy John, Vikaskumar R. Shukla, Margi A. Patel and Bijal M. Patel A series of ten derivatives of quinolin-8-yl[(5-aryl-1,3,4-oxadiazol-2 -yl)sulfanyl]acetate was designed and derived through various steps. The structures of synthesized compounds were determined by IR, 1H NMR and Mass spectroscopy analyses. The antibacterial strength of synthesized compounds was evaluated by using bacterial strains Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli where the study data reveals that some of the compounds have good antibacterial potential.Click Here To Read More 71-75 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.012

13. Development of a High Performance Liquid Chromatography Method for the Determination of Related Substances in a Liposomal Nano Pharmaceutical Using Quality by Design Approach S. N. Deshpande, M. Farooqui, G. Sanap and D. D. Kayande This study presents the development of gradient reverse phase high performance liquid chromatographic method for the determination of Doxorubicin hydrochloride and its five impurities following Quality by Design (QbD) approach and also to identify the conditions where adequate separation quality in minimal analysis duration could be achieved within a robust region that guarantees the stability of method performance. The relationship between critical process parameters and critical quality attributes is created applying Design of Experiments methodology.Click Here To Read More 76-84 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.013

14. Synthesis, Characterization and Biological Evaluation of Novel N-alkylated 2-(4-bromophenyl)-1H-benzimidazole Derivatives Deshmukh S. K. and Sanjay Dashrath Vaidya In present study O-pheylenediamine and 4–bromo benzoic acid were used as starting material and treated with poly phosphoric acid to obtained 2-(4-bromophenyl)-1H-benzimidazole.Using this compound, alkylation done at the benzimidazole –NH position with different benzyl halide reagent leading to the functionalized derivatives. Newly synthesized derivatives (5a to 5g) have been evaluated on the basis of spectral and analytical data like melting point, IR, 1H-NMR and Mass spectroscopy.Click Here To Read More 85-90 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.014

15. Determination of Metal-Ligand Stability Constant of Transition Metal Complexes with Pharmacologically Active Ligand N-[(E)-(2-Nitrophenyl)methylen]isonicotinohydrazid Zamzam Taher Omar (Al-Ahdal), Shivaji L. Jadhav and Megha J. Rai Proton–ligand association constants of organic ligand N-[(E)-(2-Nitrophenyl) methylen]isonicotinohydrazid with Mn (II), Co (II), Ni (II), Cu (II) and Zn (II) metal ions have been studied by pH-metric technique at 27±1ͦC in 70%(v/v) ethanol – water medium at 1M (NaClO4) ionic strength. Organic ligand was synthesized by condensation of equimolar mixture of Anti-mycobacterial agent with aromatic aldehyde. The reaction progress and purity of organic ligands were confirmed by thin layer chromatography. Formation of organic ligands was confirmed with the help of MP, IR, 1H NMR, 13C NMR and elemental analysis.Click Here To Read More 91-95 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.015

16. Threat Categorization of Floristic Diversity of Murari Devi and Surrounding Areas in Mandi District of Himachal Pradesh, India Pankaj Sharma Mountains are home to some of the world’s most threatened and endemic species (including medicinal plants), as well as to some of the poorest people, who are dependent on the biological resources. Therefore, present attempt has been made to assess the threat categories of species in Murari Devi and surrounding areas and suggest conservation options. A total 80 species (32 Trees; 28 Shrubs and 20 Herbs) belonging to 68 genera and 46 families have been identified as threatened from Murari Devi and surrounding areas.Click Here To Read More 96-104 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.016

17. Stability Constant Study of Transition Metal Complexes with Pharmacologically Active Nicotinamide and Alanine by pH Metric Technique D. D.Kayande, Shivaji Jadhav, Mazahar Farooqui and Megha Rai The main objective of this research work is to carry out the stability constant study of ternary complexes of transition elements with nicotinamide and alanine. Formation of ternary complexes of transition elements like Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) of pharmacologically active Nicotinamide with Alanine was studied by the pH-metric technique at 25±0.1°C in 70%(v/v) ethanol – water medium at 0.1M (NaClO4) ionic strength.Click Here To Read More 105-107 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.017

18. Synthesis, Characterization and Antifungal Activity of Metal Complexes having Hydrazinobenzimidazole Based Ligands Anand Mohan Jha, Vishwa Deepak Tripathi, Nidhi Jha & Ajoy Mishra The synthesis, characterization and antifungal activity of some transition metal complexes of N1–{(1E)-1H-benzimidazol-2-yl) benzylidene-2-hydrazinobenzimidazole} (Bbhbz) of composition M(Bbhbz)X2 (X=Clˉ or Brˉ) for Cu2+ and (X= Clˉ, Brˉ, Iˉ and NCS) for Zn2+ or Cd2+ and M(Bbhbz)X2 (M= Ni2+, Co2+ or Mn2+ and X=Cl or 1/2SO4) have been reported. The electrical conductance, Magnetic Susceptibility, IR and electronic absorption spectra of mono ligated complexes M(Bbhbz)X2 are consistent with five coordinated trigonal bipyramidal structure while those of bis ligated complexes M(Bbhbz)X2 (M= Mn2+, Ni2+ and Co2+) are pseudo octahedral.Click Here To Read More 108-113 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.018

19. Supercritical Fluid Extraction: A Review Tariq Ahmad, F. A. Masoodi, Sajad A. Rather, S. M. Wani & Amir Gull Supercritical fluid Extraction (SFE) is a green technology as use of supercritical CO2 (SC-CO2) is the most widely used since it is nontoxic, non-flammable, non-corrosive, and easy to handle allowing supercritical operation at low pressures and near room temperature. Supercritical CO2 (SC-CO2) is cheap and readily available in bulk quantities with a high degree of purity, ensuring minimal alteration of the bioactive compounds and to preserve their curative or functional properties, possesses the ability to solubilize lipophilic substances, and can be easily removed from the final products. It is environmentally friendly and “generally recognized as safe “GRAS” technique.Click Here To Read More 114-122 [DOWNLOAD PDF]

[FULL TEXT HTML]

[DOI]: http://dx.doi.org/10.33980/jbcc.2019.v05i01.019

20. Click Here To Read More [DOWNLOAD PDF]

[FULL TEXT HTML]
[DOI]: http://

Leave a Reply

Your email address will not be published. Required fields are marked *