Volume 4 Issue 2

Sr. No. Title Author’s Name(s) Abstract Page Number Article PDF
1. Synthesis of Novel Methoxy Substituted Benzothiazole Derivatives and Antibacterial activity against Streptococcus Pyogene Akhilesh Gupta Streptococcus (S) pyogenes is a Gram-positive facultative anaerobic organism which occurs in chains or in pairs and rarely cause life-threatening infection. Transmission of S. pyogenes is usually through direct contact with droplets of saliva or nasal secretions from carriers or persons with clinical infection, or through skin contact, especially contact with infected lesions. Synthesis and screening of benzothiazole derivatives have great importance in heterocyclic chemistry because of its potent and significant biological activities against Streptococcus (S) pyogenes especially methoxy substitution at benzothiazole. Methoxy substituted benzothiazole derivatives were synthesized by reaction of 3-chloro-4-methoxy-aniline with potassium thiocyanate under temperature control and presence of bromine in glacial acetic acid and ammonia.Click Here To Read More 01-06 DOWNLOAD PDF

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2. Synthesis and Pharmacological Activity of Metal Complexes having Hydrazinobenzimidazole Based Ligands Anand Mohan Jha, Madhu Bala, K. K. Jha & L. K. Mishra The complexes of N1-{(1E)-1H–benzimidazol–2–yl) ethylidene 2 hydrazinobenzimidazole} (BahbH) with some transition metal ions of composition, M(BahbH)2Cl2 (M=MnII, CoII, NiII), [M (BahbH)X2] (M=CuII and X=Cl– or Br–, when M=ZnII, CdII, X=Cl or I) Cu (BahbH)I, Ag (BahbH) NO3, [M(BahbH)2] SO4.nH2O (M=MnII, CoII or NiII and n=1 or 2) have been prepared and characterized by elemental analysis, and studies of IR, UV, Magnetic susceptibility values and electrical conductance measurements at room temperature. The magnetic and spectral properties of MnII, CoII and NiII complexes are consistent with octahedral structure.Click Here To Read More 07-14 DOWNLOAD PDF

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3. Development and Validation of New Methods for Concentration of Vegetables and Fruit Juice Noopur Mahawar & IKram Qureshi Evaporation, when the juice is heated in vacuum in the appropriate trays, but this heat does not reach the boiling point, since during the boiling process all the useful substances will be destroyed. Currently, juice concentrates are produced by separating the water from the fresh juice. One of the following methods is used for the production of juice concentrates: evaporation of the freezing water or of the diaphragm method. The article represents the use of a new method developed for the production of juice concentrate, in which the water does not move away, but the water itself provides the production of the freezing process, repeating the evaporation completely, except of the temperature parameters.Click Here To Read More 15-18 DOWNLOAD PDF

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4. Nutritional Value and Elemental Analysis of Katphala (Myrica esculenta Buch-Ham) Atul Kabra & Uttam Singh Baghel Myrica esculenta (Family: Myricaceae) commonly known as Kaiphala or Katphala is a widely used medicinal plant in Ayurveda. Traditionally its leaves are used in the treatment of fever, catarrh of mucous membrane, asthma, diarrhoea and bronchitis, its paste is applied to cuts and wounds. In spite of its numerous medicinal attributes, no published work is available till date on nutritional values and elemental analysis of leaves. The nutrient and antinutrient compositions of the leaves were investigated and compare the evaluated data with reported nutritional parameters of fruit. The result of proximate analysis shows that Myrica fruit had higher moisture content, crude lipids and carbohydrate contents values of 72.33±0.23, 4.93±0.06 % and 78.03±0.14 % while those of the leaves had 3.54±0.11 %, 1.38±0.54 % and 46.19±0.21 %.Click Here To Read More 19-25 DOWNLOAD PDF

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5. Analytical Study of Residual Solvents in Levalbuterol Sulphate by Gas Chromatography Piyush M. Maurya The purpose of this research study was to develop and optimize an accurate and precise GC method for the determination of Residual solvents (Methanol, Isopropyl alcohol, Dichloromethane, Ethyl acetate, Tetrahydrofuran, Toluene) in Levalbuterol Sulphate. The method optimized on BP-624, 30 m x 0.32mm ID, 1.8 μm column as stationary phase. The injection volume of samples taken was 1.2 ml with split less injection. The temperature maintained at the injector and detector was to be 220ºC and 260ºC respectively. Nitrogen gas was used as mobile phase and the detection was done by FID.Click Here To Read More 26-30 DOWNLOAD PDF

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6. Isolation and Characterisation by Proteus vulgaris from Mangrove Sediment of Vellar Estuary for Urease Production A. Rebekkah Shanthakumari and M. Boominathan Urease is a virulence factor found in various pathogenic bacteria. It is essential in colonization of a host organism and in maintenance of bacterial cells in tissues. Due to its enzymatic activity, urease has a toxic effect on human cells. The present study focused on the production of urease by a Proteus vulgaris isolated from a sediment sample of Vellar estuary, Porto Novo, Tamil Nadu, India. Secondary screening for quantitative urease estimation was done by phenol-hypochlorite assay. Based on the maximum enzyme activity on urease slant and plate assay as well as quantitative biochemical enzyme assay, most potential strains were chosen for further studies.Click Here To Read More 31-35 DOWNLOAD PDF

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7. Novel Analytical Method Development and Validation for Estimation of Clinical Important Rosuvastatin in Bulk and Pharmaceutical Dosage Form by UV Spectroscopy Method Using Phosphate Buffer Solubility Suvarna G. Bhokare and R.P. Marathe Biosynthesis of cholesterol is a natural phenomenon and gets completed in lever in 25 steps. Disorder in any of the steps may cause over or under production of cholesterol that may lead ultimately to atherosclerosis, thrombosis or coronary artery disease, depending on disorder. Statins are the class of drugs that inhibit HMG CoA reductase, a rate limiting enzyme, competitively during mevalonate pathway in the synthesis of cholesterol in hepatocytes. Rosuvastatin is a synthetic drug of this class. It is newer drug with 20% bioavailability and 19 hours elimination half-life.Click Here To Read More 36-40 DOWNLOAD PDF

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8. Variations in Physicochemical Parameters and Distribution of Mycoflora in Rhizospheric Soil due to Charcoal Rot of Jowar (Sorghum bicolor L.) M. T. Gavali, Mane S. R., Kumbhar V. R., Birajdar G. M. and U. N. Bhale Jowar (Sorghum bicolor L.) plant belongs to family poaceae is cultivated in warm climates worldwide and it is inhabitant to the tropics and subtropics region. The present investigation was studied physicochemical characterization and rhizosphere soil mycoflora in the field of jowar charcoal rot caused by Macrophomina phaseolina. Mycoflora of infected field of jowar, need to improve the knowledge of diversity of fungi associated with infected rhizosphere soil. Physico-chemical analyses of infected rhizosphere soil were studied by standard soil testing methods and fungal population dynamics by using soil dilution technique.Click Here To Read More 41-47 DOWNLOAD PDF

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9. Synthesis of Resorufin Based Chromogenic and Fluorescent Probe for Detection of Mercury Milind Shamrao Thakare and Pravin Madhavrao Yeole Mercury in its lipophilic and inorganic form is a major threat to the environment and to human health. It is therefore highly necessary to develop a chemosensor for mercury detection. A novel fluorescent probe for mercury, 7-(vinyloxy)-3H-phenoxazin-3-one has been designed and synthesized by anchoring resorufin (helping as a fluorophore ) with vinylic ether moiety. In present work we have designed a fluorescence strategy based on the π-electrophilicity. The Probe is essentially nonfluorescent which upon reaction with Hg(II) undergoes oxymercuration of vinylic doublebond followed by cleavage, complemented by the generation of strong fluorescence to detect traces of mercury in biological samples.Click Here To Read More 48-53 DOWNLOAD PDF

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10. Storage-dependent Detection of Germination Inhibitors in Seeds of Aconitum heterophyllum Wall ex Royle from Kinnaur (Himahcal Pradesh) Vinay Kumar Remarkably, the dormancy status could vary even within a species, depending upon the factors such as differences between individuals, location, climatic conditions as well as nature and duration of seed storage after collection. Apparently, seed dormancy is of immense significance in ensuring the survival of plant species during adverse conditions. However, it hampers the seed germination that turns out to be a disadvantage for the seed based propagation/cultivation of plant species. The full realization of the potential of seeds in achieving plant regeneration/cultivation of a plant species depends to a great extent on the understanding of the basic mechanism(s) of dormancy.Click Here To Read More 54-58 DOWNLOAD PDF

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11. Design and Synthesis of Heterocyclic Curcumin Analogues as Filarial Topoisomerase II Inhibitors Vishwa Deepak Tripathi & Anand Mohan Jha series of novel heterocyclic curcumin analogues (substituted cinnamoyl-4-hydroxy-6 methyl-2Hpyran- 2-one derivatives 3-24), were designed and synthesized via condensation of different benzaldehydes and dehydroacetic acid. A new way for modification of curcumin has been described in order achieves enhanced pharmacological properties. Synthesized derivatives were also evaluated for their inhibitory activity against filarial topoisomerase II enzyme. All the compounds screened against Topoisomerase II exhibited excellent inhibition upto percentage inhibition more than 95%. Further the structure–activity relationships of the cinnamoyl 4-hydroxy-6- methyl-2H-pyran-2-one derivatives (3-24) reveals that among the synthesized compounds, the nitro substituted chalcones derivatives 5 and 8 were the most active compounds by showing significant inhibition of S. cervi Topoisomerase II activity upto more than 95%.Click Here To Read More 59-64 DOWNLOAD PDF

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12. Synthesis of Carbethoxycinnoline Derivatives and Antimicrobial Evaluation Komal Jakhar 3-Carbethoxy-6-substituted-4-methylcinnolines have been synthesized by cyclization of phenylhydrazonocarbethoxyacetones under microwave irradiations using polyphosphoric acid as condensing agent. The phenylhydrazonocarbethoxyacetones are prepared from benzenediazonium chloride and ethylacetoacetate. The antibacterial potential of the title compounds has been described against different bacteria’s.Click Here To Read More 65-69 DOWNLOAD PDF

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13. Essential Oil Extraction, Characterization and Antimicrobial Study of Blumea laciniata DC from Konkan Region Abhijit V. Dinde, P. B. Lokhande & H. A. Mujawar The present study of Essential Oil of Blumea laciniata DC was designed to evaluate essential oil extraction, phytochemical composition and Anti-Microbial Study of essential oil from Blumea laciniata DC collected from Dapoli Tehsil in Konkan Region. The Essential Oil was extracted by methods using like Hydro distillation using Clevenger’s type Apparatus, Steam Distillation and Solvent Extraction. Characterization of essential oil was done by IR, GC-MS and Anti-Microbial Activity.Click Here To Read More 70-76 DOWNLOAD PDF

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14. Autochthonous Bacterial Community in Remediation of Azo Dyes: A Review T. Sheela, Baby Jooju and S. Senthil Kumar Azo dyes are one of the most widely used chemical class of dyes and colorants of textile industry used to color natural and synthetic fibers. Structurally molecules of azo dyes contain two adjacent nitrogen atoms between carbon atoms. About 60-70% of dyes used in the food and textile industry are of azo dyes as they provide strong and variety of colours. Apart from holding a key position in textile industry, azo dyes create several problems as pollutants to living beings and environment. Their presence in textile effluent is a major problem due to their adverse effects. Several of the degradation products of the azo dyes have been found to be mutagenic and carcinogenic. There are number of proposed remedial measures for the treatment of waste water effluents containing azo dyes generated by various industries.Click Here To Read More 77-85 DOWNLOAD PDF

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15. Nutritional Qualities and Host Specificity of Most Common Edible Macrofungi of Hamirpur District, Himachal Pradesh Jyoti Pathania and Hem Chander This paper analyses nutritional qualities and host specificity of most common edible macrofungi of Hamirpur district, Himachal Pradesh. During the ongoing studies on diversity of macrofungi, specimens of edible fungi were randomly collected from twelve localities (viz. Chheorin, Doh, Baru, Bohni, Saloni, Bhota, Tikkarkhattriyan, Kohin, Tikkar-sujanpur, Doli-sujanpur, Harson and Fafan) of Hamirpur region and five species of most common edible macrofungi viz. Auricularia auricula-judae, Ganoderma applanatum, Ganoderma lucidum, Pleurotus ostreatus and Schizophyllum commune were identified. The chemical composition of these macrofungi include ash, protein, fats, carbohydrates, glucose, mannose, xylose, galactose, amino acids, fibre, phosphorus, magnesium, calcium, iron, zinc, magnesium, copper and chromium.Click Here To Read More 86-89 DOWNLOAD PDF

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16. Assessment of Ground Water Quality of Agricultural Land for Irrigation Purpose in Some Villages of Akola District of Maharashtra, India Pradip P. Deohate Assessment of ground water quality of agricultural land for irrigation purpose in Gram-Kolvihir, Kumbhari and Shivapur of Akola district of Maharashtra, India was carried out to evaluate the factors regulating ground water quality. Total fifteen samples of the ground water were drawn from the open wells in the month of September-2017 and analyzed for various physico-chemical parameters such as temperature, colour, pH, EC, alkalinity, chloride, sulphate, calcium, magnesium, sodium, potassium, TDS, COD, DO and BOD. Sodium hazard associated with the irrigation water was judged using SSP and SAR criteria.Click Here To Read More 90-94 DOWNLOAD PDF

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17. Ferrous Sulphate Catalysed Synthesis of 1, 5-Benzothiazepines using Sonication Method Priti Pawar, Vitthal S. Shivankar, Yashwant A. Gaikwad, Shakuntala S. Patil & Gurumeet C. Wadhawa One step synthesis of various aromatic substituted, 1-5-benzothiazepines carried by the reaction of different substituted chalcone with ortho-aminothiophenol in sonication at 40ºC using ferrous sulphate as catalyst. This reaction method is mild reaction condition and has very short reaction time as compared to the other conventional methods. The structural assignment of the final product has been done by spectral techniques or other techniques.Click Here To Read More 95-98 DOWNLOAD PDF

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18. Synthesis of Chelating Resin with Schiff base and its Coordination Compounds with Copper (II), Nickel (II), Cobalt (II), Iron (III), Zinc (II), Molybdenum (VI) and Uranium (VI) Geeta Solanki, Vikas Malik & Dr Munesh The polymer-anchored ligand polystyrene bound schiff base (1) was prepared from 3 aldehydo-4-hydroxy diphenyl and amino methylated polystyrene in 100% in DMF solvent & the reaction of polymer anchored legend & metal complex or metal salt leads to a colour change from cream to yellow, green, yellowish except in the Cd (II) & Zn (II) complexes where no such change was observed. The polymer-anchored ligand (1) exhibits a band at 1650 cm-1 due to the v (C=N) which shifts to lower energy by 20-25 cm-1 in the polymer anchored complexes indicating nitrogen coordination of the ligand.Click Here To Read More 99-103 DOWNLOAD PDF

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19. An Enumeration of Lichenized Fungi from Sikandra Dhar Region of District Mandi, Himachal Pradesh Monika Thakur and Hem Chander Floristic studies have been initiated to explore diversity of lichenized fungi in Sikandra dhar region of district Mandi, Himachal Pradesh (India). Sikandra dhar region is situated in Shivalik hills zone of North-West Himalaya. A total of three hundred specimens of lichenized fungi were collected from Sikandra dhar region. During the morpho-chemotaxonomic investigations, a total of twenty five species of lichens (Aspicilia calcarea (L.) Körb., Brianaria bauschiana (Körb.) S. Ekman & M. Svenss., Candelaria concolor (Dicks.) Arnold, Canoparmelia pustulescens (Kurok.) Elix, Chrysothrix candelaris (L.) J.R. Laundon, C. chlorina (Ach.) J.R. Laundon, Cladonia coniocraea (Flörke) Spreng, Dermatocarpon vellereum Zschacke, Heterodermia pseudospeciosa (Kurok.) W.L. Culb, Hyperphyscia syncolla (Tuck. ex Nyl.) Kalb…Click Here To Read More 104-116 DOWNLOAD PDF

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20. Combined Treatment Method for the Remediation of Fe2+, PO4, SO4 and NO3 from River Patalganga Sushama S. Darade & N. N. Bandela The generalized use of Bermuda grass extract for medicinal purposes is common whereas the phytoremediation of soil and water for the accumulation of heavy metals is a traditional method in the field of waste water treatment. The current paper presents a combined treatment method for the remediation of Fe2+, PO4, SO4, and NO3. The laboratory scale work resulted in a novel technique in which the methanolic extract of Bermuda grass and the biochar obtained after the methanolic extraction process had the potential of removing NO3> SO4>Fe2+> PO4 from the Patalganga River water under investigation.Click Here To Read More 117-123 DOWNLOAD PDF

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21. Determination of Physico-Chemical Parameters of Ground Water Used for Irrigation in Villages of Akola District of Maharashtra, India Pradip P. Deohate Determination of physico-chemical parameters of ground water used for irrigation in Gram-Babhulgaon and Chandur of Akola district of Maharashtra, India was worked out to evaluate the factors that regulate ground water quality. In the month of February-2016, ten ground water samples from open wells were assessed for parameters i.e. temperature, colour, pH, EC, alkalinity, chloride, sulphate, calcium, magnesium, sodium, potassium, TDS, COD, DO and BOD. Using SSP and SAR criteria, sodium hazard associated with the irrigation water was evaluated.Click Here To Read More 124-127 DOWNLOAD PDF

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22. Preparation and Characterization of Binuclear Complexes of NN’NN’’ tetrakis (2-methylbenzimedazolyl) p-phenylenediamine with Zn (II) and Cd (II) Irshad Ali, Madhu Bala, Md. Athar Shadiq & Faisal Farooq The binuclear complexes of NN’NN’’ tetrakis (2-methylbenzimedazolyl) p phenylenediamine (L) with Zn (II) and Cd (II) having composition M2LX4 (M=ZnII and CdII, X=Cl¯, NCS¯ and CH3COO¯) have been prepared and characterized from the studies of elemental analysis, electrical conductance measurement, magnetic susceptibility, UV and IR spectral analysis. The electrical conductance value of complexes in DMF shows negligible electrical conductance value at 30ºC (~ 10-12 Ohm-1 mol-1 cm2) supported the coordination of anions with metal ions. IR data of thiocyanato complexes suggested N-bonding of NCS group in Zn (II) and through S atom in Cd (II) complexes.Click Here To Read More 128-130 DOWNLOAD PDF

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23. Apparent Molar Volume and Expansibility Behaviour of Magnesium, Calcium and Strontium caprate in Non-aqueous Medium Chitra Singh and S. K. Upadhyaya The density measurements of magnesium, calcium and strontium caprate in non- aqueous medium at different temperatures (25-40º C) has been used to evaluate various significant parameters viz. apparent molar volume (v ),and expansibility (E0 soap ) to study their solution behaviour. The critical miceller concentration (CMC), is found to decrease with increasing temperature and vary with different metals as Mg>Ca>Sr. The density of these soap solutions increases with increasing concentration and decreasing temperature.Click Here To Read More 131-135 DOWNLOAD PDF

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24. Species Diversity of Arbuscular Mycorrhizal Fungi (AMF) in the Rhizospheric Soil of Spilanthes acmella Murr. Chhavi Mangla, Aditya Kumar and Ashok Aggarwal Microbes are very important components of soil plant complex where they show a network of interactions affecting plant health, growth and development. In the present investigation, attempts were made to screen out arbuscular mycorrhizal fungal (AMF) species from rhizospheric soil of Spilanthes acmella- an important medicinal plant. A total of ten species of arbuscular mycorrhizal (AM) spores were screened out.Click Here To Read More 136-139 DOWNLOAD PDF

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